Search on: PULMONARY SURFACTANT ASSOCIATED PROTEIN SP C 
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Descriptor English:   Pulmonary Surfactant-Associated Protein C 
Descriptor Spanish:   Proteína C Asociada a Surfactante Pulmonar 
Descriptor Portuguese:   Proteína C Associada a Surfactante Pulmonar 
Synonyms English:   Pulmonary Surfactant Protein C
SP-C protein
Surfactant Polypeptide SP-C
Pulmonary Surfactant Associated Protein C
Pulmonary Surfactant Associated Protein SP C
SP C protein
SP-C, Surfactant Polypeptide
Surfactant Polypeptide SP C
Pulmonary Surfactant-Associated Protein SP-C  
Tree Number:   D12.776.543.717
D12.776.816.750
D12.776.823.186
Definition English:   A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers. 
Indexing Annotation English:   DF: SP-C PROTEIN
Pharmacological Action:   Pulmonary Surfactants
 
History Note English:   2003; use PULMONARY SURFACTANT-ASSOCIATED PROTEIN C (NM) 1990-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37474 
Unique Identifier:   D037721 

Occurrence in VHL:
 

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